Let's take a look at other people's comics.
Comics I like:
Dinosaur Comics - http://qwantz.com/ - simple and witty. Me likey
Whispered Apologies - http://www.qwantz.com/apologies/ - Collaboration work between different artists. Some are HALLAREOUS!
Perry Bible Fellowship - http://pbfcomics.com/?comic=random - LOLZZ!!
Dresden Codak - http://dresdencodak.com/archives/ - Troublingly philosophical. I have no idea what they're talking about, but I like the graphics style. Also there's a tiny Carl Jung.
Wondermark! - http://wondermark.com/ - LOLOL
Flaky Pastry - http://flakypastry.runningwithpencils.com/archive.php - A nice story that doesn't suck!
Copper - http://www.boltcity.com/copper/ - Don't care for the story but I like the style.
Comics I don't like:
Questionable Content - http://questionablecontent.net./index.php - A story featuring less guys than girls, and indie rock culture jokes. Most of it is based on a weak sexual tension, based on the fact that the guy doesn't get to bang the chicks that enter his apartment until much later in the story, and even then there's tension between him and the chicks he hasn't banged yet. The problem here was that it's very transparent. Well screw it. The whole thing could end with a frickin gang bang.
Fredo and Pidjin - http://www.pidjin.net/ - Cheap, narrowminded and shallow jokes. The religion jokes are, to say the least, underdocumented. The sex jokes are also shallow and unimaginative. They sometimes get a cheap and fast laugh, but no more.